[HTML][HTML] Immune cell therapy for hepatocellular carcinoma
E Mizukoshi, S Kaneko - Journal of hematology & oncology, 2019 - Springer
… respective T cell epitopes, thus confirming the presence of T cell-… frequency and function of
NK cells in the peripheral blood … polyclonal T cells, both CD4 + and CD8 + T cells, and T cells …
NK cells in the peripheral blood … polyclonal T cells, both CD4 + and CD8 + T cells, and T cells …
[HTML][HTML] Hepatocellular carcinoma immune landscape and the potential of immunotherapies
… with poorer differentiation, higher tumor grade, the presence of … tumor-infiltrating CD8 + T
cells are significantly correlated … that higher intratumoral frequency of PD-1 high CD8 + T cells (…
cells are significantly correlated … that higher intratumoral frequency of PD-1 high CD8 + T cells (…
Induction of specific CD8 (+) T cells against hepatocellular carcinoma-associated neoantigens
YM Wang, BH Zhao, K Chen, ZJ Li… - Zhonghua Zhong liu za zhi …, 2019 - europepmc.org
… , we used NetMHC software to predict the neoantigen epitopes with high binding affinity to
… existed relative higher mutation frequency in HCC, and expressed higher in tumor tissues. …
… existed relative higher mutation frequency in HCC, and expressed higher in tumor tissues. …
[HTML][HTML] Uncovering the tumor antigen landscape: what to know about the discovery process
… T cell epitope algorithms that are able to predict putative T … In addition, a p53 derived wild
type peptide (L9V) was used to … of epitopes recognized by CD8+ T cells a priority in the cancer …
type peptide (L9V) was used to … of epitopes recognized by CD8+ T cells a priority in the cancer …
[HTML][HTML] Targeting immune cells in the tumor microenvironment of HCC: new opportunities and challenges
X Hao, G Sun, Y Zhang, X Kong, D Rong… - Frontiers in cell and …, 2021 - frontiersin.org
… When CD8 + T cells recognize antibodies on DC, CD80 − … The frequency of circulating PD-1
(+) CD8 (+) T cells increases as … be much higher in tumor-infiltrating CD8 (+) T cells. In vitro, …
(+) CD8 (+) T cells increases as … be much higher in tumor-infiltrating CD8 (+) T cells. In vitro, …
Developing anti-p53/HLA-A* 0201 T-cell receptor mimic antibodies for cancer immunotherapy
I Trenevska - 2019 - ora.ox.ac.uk
… wild type p53 rather than mutated p53 epitopes ............ 50 1.5 … Once at the cell surface, the
TCR of CD8+ T cells recognises … peptide by MHC-I can all affect the epitope density at the cell …
TCR of CD8+ T cells recognises … peptide by MHC-I can all affect the epitope density at the cell …
[HTML][HTML] Prospects for immunotherapy as a novel therapeutic strategy against hepatocellular carcinoma
Y Akazawa, T Suzuki, T Yoshikawa, S Mizuno… - World Journal of Meta …, 2019 - wjgnet.com
… Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes
in peripheral blood correlate with presence of epitope loss tumor variants in patients with …
in peripheral blood correlate with presence of epitope loss tumor variants in patients with …
[HTML][HTML] The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer
C Gouttefangeas, R Klein, A Maia - Frontiers in Immunology, 2023 - frontiersin.org
… from CD8 + T cells), leads to inflammation and tissue damage with … CeD patients, processes
gluten to T cell reactive epitopes … when mice were injected with p53-derived peptides. In this …
gluten to T cell reactive epitopes … when mice were injected with p53-derived peptides. In this …
[HTML][HTML] p53: from fundamental biology to clinical applications in cancer
M Capuozzo, M Santorsola, M Bocchetti, F Perri… - Biology, 2022 - mdpi.com
… , T cells armed against wild-type p53 epitopes recognize … -chain T-cell receptor domain that
recognizes a peptide epitope … CD4+ and CD8+ T cells recognizing a p53 peptide repertoire …
recognizes a peptide epitope … CD4+ and CD8+ T cells recognizing a p53 peptide repertoire …
[HTML][HTML] Structural aspects of chemical modifications in the MHC-restricted immunopeptidome; Implications for immune recognition
… to induce CD8 + T cell responses towards a p53-derived HLA-A*24:02-restricted epitope. …
-derived and/or cancer-associated epitopes by T cells and NK cells can induce immune …
-derived and/or cancer-associated epitopes by T cells and NK cells can induce immune …